NOTCH2 anticorps (Biotin)
Aperçu rapide pour NOTCH2 anticorps (Biotin) (ABIN1169005)
Antigène
Voir toutes NOTCH2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- Recognizes human and mouse endogenous Notch-2 receptor.
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Réactivité croisée
- Humain, Souris
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Purification
- Purified from concentrated hybridoma tissue culture supernatant.
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Pureté
- >95 % (SDS-PAGE)
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Immunogène
- Recombinant mouse Notch2:Fc .
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Isotype
- IgG1
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- In PBS containing 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C. -
Date de péremption
- 12 months
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- NOTCH2 (Notch 2 (NOTCH2))
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Autre désignation
- Notch2
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Sujet
- Notch signaling pathway regulates many different cell fate decisions in both vertebrate and invertebrate species. There are 5 canonical Notch ligands in mammals: Jagged-1, Jagged-2, DLL1, DLL3 and DLL4. These can bind to the four Notch receptors Notch 1-4. It is important for pattern formation during development such as neurogenesis, angiogenesis or myogenesis and regulates T cell development and stem cell maintenance. Notch signaling is also involved in cellular processes through-out adulthood. Signaling via Notch occurs between neighbouring cells and both the receptor and its ligands are transmembrane proteins.
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UniProt
- O35516
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Pathways
- Signalisation Notch, Stem Cell Maintenance
Antigène
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